In the 1980-90s Blomhoff and Drevon were studying the metabolism and biological effects of fat-soluble vitamins A, D and E. In addition to publish several papers and educate many PhD students it was an increasing awareness of the clinical importance of the fat-soluble vitamins in fetal development, cell differentiation, bone metabolism and antioxidant defense of importance for development of cardiovascular diseases as well as cancer.
The rapid scientific progress promoted enhanced demands for measurements of the fat-soluble vitamins among patients with several types of diseases. Because Blomhoff and Drevon had analytical methods for measuring vitamin A, D and E they were often asked to measure these vitamins for clinical purposes. As the demand for these demanding analyses (in the early 1990s) enhanced the idea about creating a public company in an understanding with the University of Oslo grew strong enough to become a reality in January 1994.
Shortly after the establishment vitas entered into collaboration with the clinical central lab Fürst in Oslo doing analysis of fat soluble vitamins and methylmalonic acid (MMA) for the Norwegian primary health care.