Lipidomics is the study of lipid compounds in biological systems. Several recent studies have demonstrated that lipids are involved in many aspects of health and disease, such are cardiovascular disease, obesity, diabetes, and degenerative disorders such as Alzheimer's and Parkinson's disease.
The overall aim of lipidomics is to gain as much information about the identity and levels of different lipids present in actual tissues. With our lipidomics platform, the different classes of lipids are well separated and quantified using state-of-the-art technology such as UPLC coupled to high-resolution mass spectrometry. We have experience on applying the comprehensive lipidomics platform on a variety of different sample types like plasma/serum and whole blood, erythrocytes, tissue, saliva, etc.
To learn more about our lipidomics platform and lipid analytical services click here.
Our lipidomics analytical services may be applicable to several different types of matrices. See below for some of our developed lipidomics methods, or contact us to find out how our technology and experience can be applied in your activities.
KEY PUBLICATIONS
In publications listed below, the lipidomic platform at Vitas has been used to generate data and information about the lipidome:
"Genetic, dietary, and sex-specific regulation of hepatic ceramides and the relationship between hepatic ceramides and IR" - Journal of Lipid Research
"Plin2 deletion increases cholesteryl ester lipid droplet content and disturbs cholesterol balance in adrenal cortex" - Journal of Lipid Research
"The effects of fumonisin B 1 at the No Observed Adverse Effect Level (NOAEL) and 5-times above on the renal histology and lipidome of rats" - Food and Chemical Toxicology