Certain types of fatty acids are called essential fatty acids (EFAs), since the body does not synthesize them and must be acquired through dietary sources. Fatty acids are vital for many cellular functions and serve vital biological functions such as energy storage and inflammatory responses.
Analysis of fatty acids is useful in evaluating the nutritional intake and intestinal adsorption of fatty acids. Fatty acid profile can assess the balance between essential Omega-6 and Omega-3 fatty acids, which can indicate the need for supplementation and/or dietary modification. In addition, the fatty acid profile could be useful in medicinal/clinical studies in regards to inflammatory conditions, depression, cardiovascular risk and dietary issues.
We can perform fatty acid profiles in a vast variety of sample types such as:
Blood samples (serum/plasma, Dried Blood Spots (DBS), erythrocytes)
Tissues (Liver, intestines, muscle, nail)
Dietary fats (Egg, milk, oils).
Vitas has several years of experience in high-throughput fat acid profile analysis from DBS using state-of-the-art chromatographic technology. A typical chromatogram showing the different fatty acids in a DBS sample is shown in the figure below.